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中国人民解放军总医院
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中国人民解放军总医院老年心血管病研究所
中国科技出版传媒股份有限公司
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中华老年多器官疾病杂志编辑委员会
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创刊人 王士雯
总编辑 范利
副总编辑 陈韵岱
执行主编 叶大训
编辑部主任 王雪萍
ISSN 1671-5403
CN 11-4786
创刊时间 2002年
出版周期 月刊
邮发代号 82-408
友情链接
李宇林,顾永林,庹田,文俊杰,彭军,刘丁铭.急诊和择期经皮冠状动脉介入术后心肌修复情况的比较[J].中华老年多器官疾病杂志,2019,18(11):855~859
急诊和择期经皮冠状动脉介入术后心肌修复情况的比较
Comparison for myocardial repair after emergency and selective percutaneous coronary intervention
投稿时间:2019-05-15  
DOI:10.11915/j.issn.1671-5403.2019.11.178
中文关键词:  磁共振成像;经皮冠状动脉介入;急诊;择期
英文关键词:magnetic resonance imaging; percutaneous coronary intervention; emergency; selection The work was supported by the Innovation Project of Medical Scientific Research for Young Scholar of Sichuan Province
基金项目:四川省医学科研青年创新课题(Q17035)
作者单位E-mail
李宇林 广安市人民医院心血管内科,广安 638500 gaslyl@163.comcomparison 
顾永林 广安市人民医院心血管内科,广安 638500 gaslyl@163.comcomparison 
庹田 广安市人民医院心血管内科,广安 638500 gaslyl@163.comcomparison 
文俊杰 广安市人民医院心血管内科,广安 638500 gaslyl@163.comcomparison 
彭军 广安市人民医院心血管内科,广安 638500 gaslyl@163.comcomparison 
刘丁铭 广安市人民医院心血管内科,广安 638500 gaslyl@163.comcomparison 
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中文摘要:
      目的 探讨急诊和择期经皮冠状动脉介入(PCI)术后心肌的修复情况。方法 回顾性分析2018年1月至2019年2月广安市人民医院心血管内科住院的心肌梗死患者97例,根据行PCI术时机分为急诊PCI术组50例和择期PCI术组47例,术后3个月通过心脏磁共振成像(CMRI)评估和比较2组患者心功能和心肌修复情况,并比较术前和术后3个月肌钙蛋白I(TnI)、脑钠肽(BNP)和肌酸激酶同工酶MB(CK-MB)水平。应用SPSS 19.0统计软件对数据进行分析,根据数据类型采用t检验或χ2检验进行组间比较。相关性采用Pearson相关分析。结果 2组患者PCI术后3个月较术前左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)、梗死心肌质量、梗死心肌容积视觉评分、室壁运动异常评分、TnI、BNP和CK-MB均改善,且急诊PCI术组相比择期PCI术组患者水平低[(108.41±21.15)和(126.61±22.05)ml;(59.55±14.41)和(65.54±11.64)ml;(6.84±2.15)和(9.16±3.00)g;(6.03±2.11)和(8.15±2.32)分;(3.01±1.16)和(4.41±1.25)分;(106.84±29.98)和(122.16±32.11)g/L;(1.00±0.34)和(1.24±0.54)ng/L;(32.21±5.44)和(35.49±4.48)U/L],差异均有统计学意义(P<0.05)。Pearson相关分析结果表明,梗死心肌质量与梗死心肌容积视觉评分、室壁运动异常评分、LVEDV、LVESV正相关(r=0.411、0.354、0.306和0.341,P<0.05)。结论 急诊PCI术可显著改善心肌梗死患者心肌的功能和修复。
英文摘要:
      Objective To investigate the myocardial repair after emergency and elective percutaneous coronary intervention (PCI). Methods A retrospective study was conducted on 97 patients with myocardial infarction admitted in our department from January 2018 to February 2019. According to the timing of PCI, they were divided into emergency PCI group (n=50) and selective PCI group (n=47). Cardiac function and myocardial repair were evaluated and compared by cardiac magnetic resonance imaging (CMRI) in 3 months after operation. The levels of troponin I (TnI), brain natriuretic peptide (BNP) and creatine kinase isoenzyme-MB (CK-MB) were compared before and 3 months after operation. SPSS statistics 22.0 was used for data analysis. Student′s t test or Chi-square test was applied to make comparison between 2 groups according to the different data types. Pearson correlation analysis was also employed. Results Compared with before operation, left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), preoperative myocardial mass, visual score of myocardial volume, abnormal wall motion score, and levels of TnI, BNP and CK-MB were all improved in both groups, and the indicators were lower in the emergency PCI group than the selective PCI group [(108.41±21.15) vs (126.61±22.05)ml, (59.55±14.41 vs (65.54±11.64) ml, (6.84±2.15) vs (9.16±3.00)g, (6.03±2.11) vs (8.15±2.32) score, (3.01±1.16) vs (4.41±1.25) score, (106.84±29.98) vs (122.16±32.11)g/L, (1.00±0.34) vs (1.24±0.54)ng/L, (32.21±5.44) vs (35.49±4.48) U/L]. Pearson correlation analysis showed that myocardial quality was positively correlated with myocardial volume visual score, wall motion abnormality score, LVEDV and LVESV (r=0.411,0.354,0.306 and 0.341, P<0.05). Conclusion Emergency PCI can significantly improve myocardial function and repair in patients with myocardial infarction.
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