Research progress of angiopoietin-like protein 2 in type 2 diabetes mellitus
Received:January 03, 2019  
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DOI:10.11915/j.issn.1671-5403.2019.06.097
Key words:angiopoietin-like protein 2; insulin resistance; diabetes mellitus, type 2
Author NameAffiliationE-mail
LEI Yun-Zhen Department of Geriatrics, Xijing Hospital, Air Force Medical University, Xi’an 710032, China  
JIAN Wei-Ming Department of Geriatrics, Xijing Hospital, Air Force Medical University, Xi’an 710032, China  
HOU Li-Ming Department of Geriatrics, Xijing Hospital, Air Force Medical University, Xi’an 710032, China  
LI Jun Department of Geriatrics, Xijing Hospital, Air Force Medical University, Xi’an 710032, China  
WANG Xiao-Ming Department of Geriatrics, Xijing Hospital, Air Force Medical University, Xi’an 710032, China xmwang@fmmu.edu.cn 
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Abstract:
      Angiopoietin-like protein 2 (ANGPTL2), a secreted circulating glycoprotein, belongs to a family of proteins structurally similar to the angiopoietins. It has been reported that the expression of ANGPTL2 is associated closely with obesity, insulin resistance, type 2 diabetes mellitus and its complications. So, the molecule becomes a research hotspot in the field of diabetes mellitus. This paper reviews the biological characteristics of ANGPTL2 and its research progress in type 2 diabetes mellitus and its complications.
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