Clinical management strategy for cancer patients concomitant with coronary artery disease
  
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DOI:10.11915/j.issn.1671-5403.2019.02.029
Key words:cancer; coronary artery disease; clinical management
Author NameAffiliationE-mail
YANG Qian Department of Cardiology, First Medical Center, Chinese PLA General Hospital, Beijing 100853, China  
HU Shun-Ying Department of Cardiology, First Medical Center, Chinese PLA General Hospital, Beijing 100853, China hsylily@163.com 
CHEN Yun-Dai Department of Cardiology, First Medical Center, Chinese PLA General Hospital, Beijing 100853, China  
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Abstract:
      Cancer patients with concomitant coronary artery disease have been increasing, whose clinical management strategy has drawn much focus in oncology and cardiology. Different from pathophysiological mechanisms of coronary artery disease alone, cancer concomitant with coronary artery disease has unique pathophysiological mechanisms associated with oncogenesis and cancer treatment, posing challenges for the clinical management of such patients. First, comprehensive treatment for cancer and coronary artery disease has to be balanced with consideration of reducing morbidity and mortality due to the two diseases. Second, individual threat of the two diseases to the patient′s life has to be weighed to determine the choice between surgery for cancer removal first or intervention for coronary artery disease first followed by surgery for cancer removal. Moreover, pre- and post-operative interventions have to be considered to reduce overall risk. Those are all difficulties in clinical management of the cancer patients with coronary heart disease. This article reviews the pathogenesis of cancer patients with coronary artery disease, comprehensive management of coronary artery disease, management of coronary intervention, and optimization of evaluation and management of coronary artery disease before surgery for cancer removal, providing reference for clinical management strategy for cancer patients with coronary artery disease.
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