Research progress of regulation of the aging process by autophagy
Received:July 17, 2018  Revised:August 21, 2018
View Full Text  View/Add Comment  Download reader
DOI:10.11915/j.issn.1671-5403.2019.01.014
Key words:autophagy; aging; gene expression regulation
Author NameAffiliationE-mail
MOU Jie Department of Geriatrics, the Affiliated Hospital of Qingdao University, Qingdao 266000, China  
FENG Wen-Jing Department of Geriatrics, the Affiliated Hospital of Qingdao University, Qingdao 266000, China  
WANG Shan Department of Geriatrics, the Affiliated Hospital of Qingdao University, Qingdao 266000, China  
FENG Mei-Ping Department of Geriatrics, the Affiliated Hospital of Qingdao University, Qingdao 266000, China  
MAO Yong-Jun Department of Geriatrics, the Affiliated Hospital of Qingdao University, Qingdao 266000, China mmc168@126.com 
Hits: 160
Download times: 162
Abstract:
      Irreversible degenerative changes occur in tissues and organs as the body ages, and these changes are closely associated with disease and death. Autophagy, an important catabolic process in cells, plays a significant role in maintaining cell homeostasis and promoting longevity. Regulatory capacity of autophagy declines after aging. In this paper, we reviewed the relationship between autophagy and aging-associated diseases, claiming that the molecular mechanism of regulation of the aging process by autophagy may provide a new target for the treatment of aging-associated diseases.
Close