Received:June 04, 2019  Revised:July 18, 2019
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Key words:subclinical hypothyroidism; bone mineral density; postmenopausal women
Author NameAffiliationE-mail
JIN Feng-Zhong 第四军医大学西京医院老年病科 7849425@qq.com 
曹桂花 第四军医大学西京医院老年病科 drcaoguihua@163.com 
王琳 第四军医大学西京医院老年病科 1948620116@qq.com 
刘艳 第四军医大学西京医院老年病科 liuyanjelly@163.com 
王晓明 第四军医大学西京医院老年病科 xmwang@fmmu.edu.cn 
NING Xiao-Xuan 第四军医大学西京医院老年病科 ningxx01@fmmu.edu.cn 
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Abstract:
      Relationship between subclinical hypothyroidism and bone mineral density in postmenopausal women 【Abstract】Objective To investigate the relationship between subclinical hypothyroidism and bone mineral density (BMD) in postmenopausal women. Methods The clinical data of 138 postmenopausal women treated in our hospital from January 2015 to June 2018 were collected and divided into subclinical hypothyroidism group (68 cases) and normal thyroid function group (70 cases). Some biochemical markers were compared with bone mineral density (BMD). Results The abnormal rate of bone mineral density in hypothyroidism group was significantly higher than that in normal group (P < 0.05). The levels of serum TSH and the prevalence of TPOAb in the hypothyroidism group were higher than those in the control group (P < 0 05), but there was no significant difference between the two groups in serum ALP, Ca2 and PTH, 25-(OH) D3 (P > 0 05), but there was no significant difference between the two groups (P > 0 05). There was a negative correlation between serum TSH,TPOAb and T value in hypothyroidism group. Conclusion Subclinical hypothyroidism may cause abnormal bone mass and decrease bone mineral density in postmenopausal women. The T value of bone mineral density in postmenopausal women with subclinical hypothyroidism is influenced by serum TSH and TPOAb.
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