Research progress of miR-375in hepatocellular carcinoma
Received:April 11, 2019  Revised:May 09, 2019
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Key words:miR-375;tumour ;hepatocellular carcinoma(HCC);diagnose ;treatment
Author NameAffiliationE-mail
SHI Yu-Zhuo 甘肃中医药大学公共卫生学院 
付婷 第四军医大学军事预防医学系流行病学教研室 
思广慧 甘肃中医药大学 
邵中军 第四军医大学军事预防医学系流行病学教研室 
ZHANG Wu-Lu 第四军医大学军事预防医学系流行病学教研室 zhangweilu@ 
王新华 甘肃中医药大学 Wangxinhua1964@ 
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      Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world. Its early symptoms are hidden and its prognosis is poor. At present, there are some limitations in the early diagnosis of HCC. A lot of studies have shown that micRNA-375 is closely related to the occurrence and development of HCC. It can be used as a marker of early diagnosis or prognosis of HCC by targeting the oncogene signaling pathway. This article reviews the recent progress of miRNA-375 and HCC research, providing a theoretical basis for the early diagnosis, treatment and prognosis of HCC.