A survey of anxiety and depression status in patients on different renal function levels and age groups
Received:May 20, 2019  Revised:June 06, 2019
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Key words:renal function; aging; anxiety; depression; Hamilton anxiety rating scale; Hamilton depression rating scale
Author NameAffiliationE-mail
ZHANG Yu Department of Geriatric Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China yuzhang1994@njmu.edu.cn 
ZHAO Wei-Hong Jiangsu Province Hospital zhaoweihongny@njmu.edu.cn 
雍珍珠 Jiangsu Province Hospital smileyzz0806@njmu.edu.cn 
裴小华 Jiangsu Province Hospital pxhphoto@njmu.edu.cn 
张娟 江苏省人民医院老年肾科 378711671@qq.com 
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      Objective To observe the anxiety and depression status of hospitalized patients on different renal function levels and age groups. Methods The anxiety and depression status of 266 patients hospitalized in geriatric department of Jiangsu Province Hospital from June 2018 to April 2019 were evaluated. According to Hamilton anxiety rating scale, the patients were divided into non-anxiety group (<7 points), mild anxiety group (7-14 points) and moderate-severe anxiety group (>14 points). In the same way, they were divided into non-depression group (<7 points), mild depression group (7-17 points) and moderate-severe depression group (>17 points) on the basis of Hamilton depression rating scale. Results The estimated glomerular filtration rate (eGFR) and hemoglobin (Hb) were significantly reduced in the anxiety and depression groups (P < 0.05), and the differences among groups were statistically significant. Compared with the non-anxiety or non-depression group, the age increased markedly in the mild and moderate-severe groups, and an upward trend could be found among groups (P<0.01). There were statistically significant differences both in renal function and age among patients in different conditions(P<0.01). Multivariate regression analysis revealed that degressive renal function (OR=1.26),aging (OR=2.01) and hypertension (OR=1.82) were risk factors for anxiety symptom. The risk factors of depression symptom included decreased renal function (OR=1.88) and aging (OR=1.72). Correlation analysis showed that there was a significantly positive correlation between anxiety and depression scores (P=0.000, r=0.719). Conclusion Decreased renal function and aging are independent risk factors for anxiety and depression in patients. With the decline of renal function and aging, the incidence of various levels of anxiety and depression symptoms increases.