Association between salt intake and NAFLD in type 2 diabetes mellitus patients in North China
Received:May 16, 2019  Revised:June 20, 2019
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Key words:salt intake, Urine sodium, diabetes, NAFLD
Author NameAffiliationE-mail
Liang Yi-Fei 哈尔滨医科大学附属第一医院内分泌二病房 liangyifei0726@126.com 
Kuang Hong-Yu 哈尔滨医科大学附属第一医院内分泌科 ydyneifenmier@163.com 
秦文 哈尔滨医科大学附属第一医院内分泌科 2414658662@qq.com 
朱文博 哈尔滨医科大学附属第一医院内分泌科 hydyyzwb@163.com 
刘念娇 哈尔滨医科大学附属第一医院内分泌科 587000469@qq.com 
左姣 哈尔滨医科大学附属第一医院内分泌科 676311792@qq.com 
韩爽 哈尔滨医科大学附属第一医院内分泌科 440691222@qq.com 
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Abstract:
      Background and Purpose:This study was conduct to explore the correlation between salt intake and NAFLD in T2DM patients in northern China.Methods:Our research choose the patients who live in the northeast of China for at least 6 months ,all the patients were diagnosed as T2DM and give treatment in The First Affiliated hospital of Harbin Medical University between 2016 to 2018. We use monofactor analysis and logistic regression analysis to assess the correlation between salt intake and NAFLD in T2DM patients.Results:Spearman correlation analysis shows that there was a correlation between different levels of salt intake and NAFLD in T2DM patients (r=0.129, P<0.001). The chi-square test was used to compare the NAFLD constituent ratio among the four groups, and the difference was statistically significant (x2=18.015, P < 0.001). In logistic regression analysis, BMI, HbA1c, fasting c-peptide, fasting blood glucose and salt intake was significantly associated with NAFLD in T2DM patients (P < 0.05). Subgroup analysis was performed on gender, age, BMI, blood glucose, systolic blood pressure. The difference was statistically significant in males, aged less than 60, with BMI≥24kg/m2, fasting blood glucose≥7.0mmol/L, and systolic blood pressure≥ 130mmHg (P < 0.05).Conclusion:With the increase of salt intake,T2DM patients in northern China were suffered from an increased risk of NAFLD. It shows that the occurrence of NAFLD was significantly correlated with BMI, HbA1c, fasting c-peptide, fasting blood glucose and salt intake.
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