Hydrogen sulfide metabolism and neuroprotection
Received:December 17, 2018  Revised:December 17, 2018
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Key words:hydrogen sulfide; central nervous system diseases; neuroprotection; signaling pathway
Author NameAffiliationE-mail
ZHANG Shu-Hu Second Affiliated Hospitalof Harbin Medical University 18846014178@163.com 
LI Jing Second Affiliated Hospitalof Harbin Medical University Email:15331886892@189.cn 
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      Hydrogen sulfide (H2S) is an endogenous gas. It is the third gas signal molecule, neurotransmitter and cytoprotective agent after NO and CO. It plays an important role in various physiological processes of brain and surrounding tissues. . The role of H2S in the central nervous system and cardiovascular system has been a hot topic in recent years. To date, the role of H2S has been partially validated in a variety of cell models, Alzheimer's disease (AD), Parkinson's disease (PD), cerebral ischemia, febrile seizures (FS), etc., but further Research is still necessary. This review summarizes the research progress of H2S, focusing on the neuroprotective effects of H2S and the corresponding signaling pathways, as well as the potential therapeutic value in the clinic.