The effect of Cardiovascular implantable electronic device on tricuspid regurgitation
Received:November 30, 2018  Revised:January 07, 2019
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Key words:cardiovascular implantable electronic devices;tricuspid regurgitation;cardiovascular disease
Author NameAffiliationE-mail
shi cheng long 中国人名解放军总医院 360709428@qq.com 
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Abstract:
      Objective To study the effect of cardiovascular implantable electronic device(CIED) on tricuspid regurgitation and its mechanism. Methods One hundred and ninety-eight patients with an enrolling of complete clinic and ultrasound data were consecutively selected in Department of Cardiology in Chinese PLA General Hospital between January 2014 to December 2016. Patients underwent a permanent pacemakers(PPM),implantable cardioverter defibrillator(ICD)or cardiac resynchronization therapy(CRT) implantation in Department of Cardiology in Chinese PLA General Hospital . According to the changes of tricuspid regurgitation observed by echocardiography before and after implantation, the selected patients were divided into 146 patients with unaggravated tricuspid regurgitation and 52 patients with aggravated tricuspid regurgitation. Clinical date and echocardiography date were collected for a retrospective analysis. Their clinical and echocardiographic data were compared and analyzed by Multi-factor logistic regression analysis was made if multiple factors included. Results Hyperlipidemia and the degree of tricuspid regurgitation before CIED implantation in patients of unaggravated tricuspid regurgitation is significant different from patients of aggravated tricuspid regurgitation. Univariate logistic regression analysis was conducted on hyperlipidemia and degree of tricuspid regurgitation before CIED implantation, it showed that hyperlipidemia (P<0.01,OR:5.424,95%CI:2.371-12.406) were positively correlated with tricuspid regurgitation, the degree of tricuspid regurgitation before CIED implantation (P<0.01,OR:0.053,95%CI:0.024-0.117) was negatively correlated. Multiple logistic regression analysis showed that implantation time (P<0.01,OR:1.000) and hyperlipidemia (P<0.01,OR: 2.024) were positively correlated with tricuspid regurgitation, the degree of tricuspid regurgitation before CIED implantation (P<0.01,OR: 0.018) was negatively correlated. Conclusion CIED implantation time and hyperlipidemia can aggravate tricuspid regurgitation, The degree of tricuspid regurgitationbefore was correlated with the severity of tricuspid regurgitation after implantation.
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